Metal-dependent Glycosylation in Recombinant Metallothioneins

García Risco, Mario; González Garnica, Ana Isabel; Calatayud, Sara; López Jaramillo, Francisco Javier; Pedrini Martha, Veronika; Albalat, Ricard; Dallinger, Reinhard; Domínguez Vera, José Manuel; Palacios, Óscar; Capdevila, Mercè

doi:10.1039/D2CC05589A

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Identificadores

URI: https://hdl.handle.net/10481/90378

DOI: 10.1039/D2CC05589A

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Editorial

Royal Society of Chemistry

Fecha

2022-11-15

Referencia bibliográfica

Published version: García Risco, Mario et al. Metal-dependent Glycosylation in Recombinant Metallothioneins. Chem. Commun., 2022,58, 13755-13758. https://doi.org/10.1039/D2CC05589A

Patrocinador

Spanish Ministerio de Ciencia e Innovación; FEDER: BIO2015-67358-C2-2-P, PID2021-123258NB-I00, PID2019-111461GB-I00; Austrian Science Fund I 3032-B21; Generalitat de Catalunya 2017SGR-864, 2017SGR-1665; Junta de Andalucía PAIDI 2020 program (DOC_00791); Universitat Autònoma de Barcelona (ICP-AES, ESI-MS); University of Innsbruck

Resumen

We show for the first time glycosylation of recombinant metallothioneins (MTs) produced in E. coli. Interestingly, our results show that the glycosylation level of the recombinant MTs is inversely proportional to the degree of protein structuration, and reflects their different metal preferences.

Colecciones

FQM368 - Artículos