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Metal-dependent Glycosylation in Recombinant Metallothioneins

dc.contributor.authorGarcía Risco, Mario
dc.contributor.authorGonzález Garnica, Ana Isabel 
dc.contributor.authorCalatayud, Sara
dc.contributor.authorLópez Jaramillo, Francisco Javier 
dc.contributor.authorPedrini Martha, Veronika
dc.contributor.authorAlbalat, Ricard
dc.contributor.authorDallinger, Reinhard
dc.contributor.authorDomínguez Vera, José Manuel 
dc.contributor.authorPalacios, Óscar
dc.contributor.authorCapdevila, Mercè
dc.date.accessioned2024-04-04T07:17:49Z
dc.date.available2024-04-04T07:17:49Z
dc.date.issued2022-11-15
dc.identifier.citationPublished version: García Risco, Mario et al. Metal-dependent Glycosylation in Recombinant Metallothioneins. Chem. Commun., 2022,58, 13755-13758. https://doi.org/10.1039/D2CC05589Aes_ES
dc.identifier.urihttps://hdl.handle.net/10481/90378
dc.descriptionResearchers from Barcelona and Granada want to acknowledge the Spanish Ministerio de Ciencia e Innovación and FEDER for the projects BIO2015-67358-C2-2-P (M.C. and Ò.P.), PID2021-123258NB-I00 (R.A.) and PID2019-111461GB-I00 (J.M.D.V). This study was co-financed by a cooperation grant to R.D. from the Austrian Science Fund (DACH grant No I 3032-B21). M.C. and Ò.P. are members of the “Grup de Recerca de la Generalitat de Catalunya”, ref. 2017SGR-864, and R.A. of ref. 2017SGR-1665. M.G.-R. acknowledges to the UAB the PIF grant. A.G. acknowledges Junta de Andalucía for the postdoctoral contract within the PAIDI 2020 program (DOC_00791). We thank the Servei d’Anàlisi Química (SAQ) at the Universitat Autònoma de Barcelona (ICP-AES, ESI-MS) for allocating instrument time. R.D. and V.P.-M. are members of the Center of Molecular Biosciences of the University of Innsbruck.es_ES
dc.description.abstractWe show for the first time glycosylation of recombinant metallothioneins (MTs) produced in E. coli. Interestingly, our results show that the glycosylation level of the recombinant MTs is inversely proportional to the degree of protein structuration, and reflects their different metal preferences.es_ES
dc.description.sponsorshipSpanish Ministerio de Ciencia e Innovaciónes_ES
dc.description.sponsorshipFEDER: BIO2015-67358-C2-2-P, PID2021-123258NB-I00, PID2019-111461GB-I00es_ES
dc.description.sponsorshipAustrian Science Fund I 3032-B21es_ES
dc.description.sponsorshipGeneralitat de Catalunya 2017SGR-864, 2017SGR-1665es_ES
dc.description.sponsorshipJunta de Andalucía PAIDI 2020 program (DOC_00791)es_ES
dc.description.sponsorshipUniversitat Autònoma de Barcelona (ICP-AES, ESI-MS)es_ES
dc.description.sponsorshipUniversity of Innsbruckes_ES
dc.language.isoenges_ES
dc.publisherRoyal Society of Chemistryes_ES
dc.titleMetal-dependent Glycosylation in Recombinant Metallothioneinses_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.1039/D2CC05589A
dc.type.hasVersionAMes_ES


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