Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
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MDPI
Materia
Oleocanthal Phenolic compounds Olive oil Therapeutic properties
Date
2018-09-24Referencia bibliográfica
Segura Carretero, A.; Curiel, J.A. Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent. Int. J. Mol. Sci. 2018, 19, 2899; doi:10.3390/ijms19102899.
Sponsorship
This work was supported by the project of Spanish Ministry of Science and Innovation (AGL2015-67995-C3-2-R).Abstract
The broad number of health benefits which can be obtained from the long-term consumption
of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been studied
deeply since their discovery due to their bioactivity properties, such as Hydroxytyrosol. Similarly,
in the last decade, the special attention of researchers has been addressed to Oleocanthal (OC).
This olive oil phenolic compound has recently emerged as a potential therapeutic agent against
a variety of diseases, including cancer, inflammation, and neurodegenerative and cardiovascular
diseases. Recently, different underlying mechanisms of OC against these diseases have been explored.
This review summarizes the current literature on OC to date, and focuses on its promising bioactivities
against different disease-targets.