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Caerulines A and B, Flavonol Diacylglycosides from Persea caerulea
dc.contributor.author | Álvarez Caballero, Juan Manuel | |
dc.contributor.author | Cuca Suárez, Luis Enrique | |
dc.contributor.author | Coy Barrera, Ericsson | |
dc.contributor.author | Olmo García, Lucía | |
dc.contributor.author | García, Jesús | |
dc.contributor.author | Cruz, Mercedes de la | |
dc.contributor.author | Perez Victoria, Ignacio | |
dc.contributor.author | Reyes, Fernando | |
dc.contributor.author | Carrasco Pancorbo, Lucía | |
dc.date.accessioned | 2021-12-20T11:45:22Z | |
dc.date.available | 2021-12-20T11:45:22Z | |
dc.date.issued | 2021-11-23 | |
dc.identifier.citation | ACS Omega 2021, 6, 48, 32631–32636. [https://doi.org/10.1021/acsomega.1c04255] | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/72133 | |
dc.description | The manuscript was written through contributions of all authors. All authors have given approval to the final version of the manuscript. | es_ES |
dc.description.abstract | Two undescribed 4′-O-methylkaempferol-[3″,4″-di-p-coumaroyl]-α-l-rhamnopyranosides, caerulines A and B (1-2), along with three known 4′-O-methylkaempferol diacylrhamnosides isomers (3-5) were isolated from an ethanol extract of the leaves of Persea caerulea, a native plant growing on the Colombian Caribbean coast. The chemical structures of 1 and 2 were elucidated by spectroscopic methods. The effect of compounds 1-5 against four pathogenic microorganisms [i.e., methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, Candida albicans, and Aspergillus fumigatus] was tested in vitro. The compounds exhibited no activity against these pathogens except MRSA (MIC 12-48 μg/mL). Caeruline B (2) was found to be the most active compound with a modest anti-MRSA activity (MIC = 12 μg/mL). | es_ES |
dc.description.sponsorship | Fundación MEDINA | es_ES |
dc.description.sponsorship | Universidad Nacional de Colombia | es_ES |
dc.description.sponsorship | Universidad del Magdalena proyecto VIN2016225 | es_ES |
dc.description.sponsorship | UMNG proyecto IMP-CIAS-2924 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | ACS | es_ES |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.title | Caerulines A and B, Flavonol Diacylglycosides from Persea caerulea | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.1021/acsomega.1c04255 | |
dc.type.hasVersion | VoR | es_ES |