Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude
Metadatos
Mostrar el registro completo del ítemAutor
Benavente Bardera, Cristina; León López, Josefa; Feriche Fernández-Castanys, María Belén; Schoenfeld, Brad J.; Bonitch Góngora, Juan Germán; Sousa Fernandes Alcobia de Almeida, Filipa; Pérez Regalado, Sergio; Padial Puche, PaulinoEditorial
MDPI
Materia
Strength Cytokines MiRNA Terrestrial altitude Hypoxia
Fecha
2021-04-16Referencia bibliográfica
Benavente, C.; León, J.; Feriche, B.; Schoenfeld, B.J.; Bonitch-Góngora, J.; Almeida, F.; Pérez-Regalado, S.; Padial, P. Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude. Int. J. Environ. Res. Public Health 2021, 18, 4233. [https://doi.org/10.3390/ijerph18084233]
Patrocinador
Spanish Ministry of Science, Innovation and Universities PGC2018-097388-B-I00; Andalusian FEDER Operational Program A-SEJ-246-UGR18; FPU pre-doctoral FPU18/00686Resumen
This study investigated the effect of a traditional hypertrophy-oriented resistance training (R-T) session at acute terrestrial hypoxia on inflammatory, hormonal, and the expression of miR-378 responses associated with muscular gains. In a counterbalanced fashion, 13 resistance trained males completed a hypertrophic R-T session at both moderate-altitude (H; 2320 m asl) and under normoxic conditions (N; <700 m asl). Venous blood samples were taken before and throughout the 30 min post-exercise period for determination of cytokines (IL6, IL10, TNF alpha), hormones (growth hormone [GH], cortisol [C], testosterone), and miR-378. Both exercise conditions stimulated GH and C release, while miR-378, testosterone, and inflammatory responses remained near basal conditions. At H, the R-T session produced a moderate to large but nonsignificant increase in the absolute peak values of the studied cytokines. miR-378 revealed a moderate association with GH (r = 0.65; p = 0.026 and r = -0.59; p = 0.051 in N and H, respectively) and C (r = 0.61; p = 0.035 and r = 0.75; p = 0.005 in N and H, respectively). The results suggest that a R-T session at H does not differentially affect the hormonal, inflammatory, and miR-378 responses compared to N. However, the standardized mean difference detected values in the cytokines suggest an intensification of the inflammatory response in H that should be further investigated.