@misc{10481/68485,
year = {2021},
month = {4},
url = {http://hdl.handle.net/10481/68485},
abstract = {This study investigated the effect of a traditional hypertrophy-oriented resistance training (R-T) session at acute terrestrial hypoxia on inflammatory, hormonal, and the expression of miR-378 responses associated with muscular gains. In a counterbalanced fashion, 13 resistance trained males completed a hypertrophic R-T session at both moderate-altitude (H; 2320 m asl) and under normoxic conditions (N; <700 m asl). Venous blood samples were taken before and throughout the 30 min post-exercise period for determination of cytokines (IL6, IL10, TNF alpha), hormones (growth hormone [GH], cortisol [C], testosterone), and miR-378. Both exercise conditions stimulated GH and C release, while miR-378, testosterone, and inflammatory responses remained near basal conditions. At H, the R-T session produced a moderate to large but nonsignificant increase in the absolute peak values of the studied cytokines. miR-378 revealed a moderate association with GH (r = 0.65; p = 0.026 and r = -0.59; p = 0.051 in N and H, respectively) and C (r = 0.61; p = 0.035 and r = 0.75; p = 0.005 in N and H, respectively). The results suggest that a R-T session at H does not differentially affect the hormonal, inflammatory, and miR-378 responses compared to N. However, the standardized mean difference detected values in the cytokines suggest an intensification of the inflammatory response in H that should be further investigated.},
organization = {Spanish Ministry of Science, Innovation and Universities 

PGC2018-097388-B-I00},
organization = {Andalusian FEDER Operational Program 

A-SEJ-246-UGR18},
organization = {FPU pre-doctoral 

FPU18/00686},
publisher = {MDPI},
keywords = {Strength},
keywords = {Cytokines},
keywords = {MiRNA},
keywords = {Terrestrial altitude},
keywords = {Hypoxia},
title = {Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude},
doi = {10.3390/ijerph18084233},
author = {Benavente Bardera, Cristina and León López, Josefa and Feriche Fernández-Castanys, María Belén and Schoenfeld, Brad J. and Bonitch Góngora, Juan Germán and Sousa Fernandes Alcobia de Almeida, Filipa and Pérez Regalado, Sergio and Padial Puche, Paulino},
}