Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults
Metadatos
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MDPI
Materia
Dietary inflammatory index Aging Inflammation Klotho
Date
2020-01-21Referencia bibliográfica
Jurado-Fasoli, L., Castillo, M. J., & Amaro-Gahete, F. J. (2020). Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults. Nutrients, 12(2), 281.
Patrocinador
The study was supported by the Spanish Ministry of Education (FPU14/04172 and FPU15/03960), by the University of Granada UGR Research and Knowledge Transfer Fund (PPIT) 2016 (Excellence Actions Programme. Units of Scientific Excellence: Scientific Unit of Excellence on Exercise and Health [UCEES]), by the Regional Government of Andalusia, Regional Ministry of Economy, Knowledge, Enterprises and University, by the European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR and by Redes Temáticas de Investigación Cooperativa RETIC grant Red SAMID RD16/0022.Résumé
Background: Soluble Klotho (S-Klotho) is an aging suppressor with a close link with
inflammation. However, it is still unknown whether the dietary inflammatory potential is associated
with S-Klotho plasma level. We aimed to investigate the association of the Dietary Inflammatory
Index (DII) with S-Klotho plasma levels in middle-aged sedentary adults. Methods: 73 middle-aged
sedentary adults (40–65 years old) participated in the present study. DII was determined from 28
dietary items obtained by 24 h recalls and food frequency questionnaires. The S-Klotho plasma levels
were measured using a solid-phase sandwich enzyme-linked immunosorbent assay. Results: a weak
positive association was observed between DII and S-Klotho plasma levels ( B = 52.223, R2 = 0.057,
p = 0.043), which disappeared after controlling for body mass index (p = 0.057). Conclusions:
A pro-inflammatory dietary pattern measured with the DII was slightly and positively associated
with S-Klotho plasma levels in middle-aged sedentary adults.