@misc{10481/61790,
year = {2020},
month = {1},
url = {http://hdl.handle.net/10481/61790},
abstract = {Background: Soluble Klotho (S-Klotho) is an aging suppressor with a close link with
inflammation. However, it is still unknown whether the dietary inflammatory potential is associated
with S-Klotho plasma level. We aimed to investigate the association of the Dietary Inflammatory
Index (DII) with S-Klotho plasma levels in middle-aged sedentary adults. Methods: 73 middle-aged
sedentary adults (40–65 years old) participated in the present study. DII was determined from 28
dietary items obtained by 24 h recalls and food frequency questionnaires. The S-Klotho plasma levels
were measured using a solid-phase sandwich enzyme-linked immunosorbent assay. Results: a weak
positive association was observed between DII and S-Klotho plasma levels ( B = 52.223, R2 = 0.057,
p = 0.043), which disappeared after controlling for body mass index (p = 0.057). Conclusions:
A pro-inflammatory dietary pattern measured with the DII was slightly and positively associated
with S-Klotho plasma levels in middle-aged sedentary adults.},
organization = {The study was supported by the Spanish Ministry of Education (FPU14/04172 and FPU15/03960),
by the University of Granada UGR Research and Knowledge Transfer Fund (PPIT) 2016 (Excellence Actions
Programme. Units of Scientific Excellence: Scientific Unit of Excellence on Exercise and Health [UCEES]), by the
Regional Government of Andalusia, Regional Ministry of Economy, Knowledge, Enterprises and University, by the
European Regional Development Fund (ERDF), ref. SOMM17/6107/UGR and by Redes Temáticas de Investigación
Cooperativa RETIC grant Red SAMID RD16/0022.},
publisher = {MDPI},
keywords = {Dietary inflammatory index},
keywords = {Aging},
keywords = {Inflammation},
keywords = {Klotho},
title = {Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults},
doi = {10.3390/nu12020281},
author = {Jurado Fasoli, Lucas and Castillo, Manuel J. and Amaro Gahete, Francisco José},
}