Smart quick response code for multianalyte determination

Abstract

The extensive use of smartphones with point-of-care applications has bolstered the development of what has come to be known as Healthcare 4.0. The ability to track biomarker parameters has become an essential part of monitoring the evolution of certain diseases, with the potential for application with a large selection of population groups. In that vein, this work presents a multianalyte quick response (QR) colorimetric code for the real-time measurement of glucose and lactate samples using smartphones. The colorimetric QR code contains both the QR static data and the dynamic information from the sample analyses. Two correction methods are applied in order to compensate for the variation in the surrounding conditions in the determination of the biomarkers. Glucose and lactate recovery between 91 and 117% was found for assays with sweat and serum samples using a smartphone readout. The developed system demonstrates flexible measurement conditions for using in real situations.