dc.contributor.author | García Fernández, Emilio | |
dc.contributor.author | González García, María del Carmen | |
dc.contributor.author | Pernagallo, Salvatore | |
dc.contributor.author | Ruedas-Rama, Maria Jose | |
dc.contributor.author | Fara, Mario Antonio | |
dc.contributor.author | López Delgado, Francisco Javier | |
dc.contributor.author | W. Dear, James | |
dc.contributor.author | Ilyine, Hugh | |
dc.contributor.author | Ress, Cristina | |
dc.contributor.author | Díaz Mochón, Juan José | |
dc.contributor.author | Orte Gutiérrez, Ángel | |
dc.date.accessioned | 2024-12-12T12:39:56Z | |
dc.date.available | 2024-12-12T12:39:56Z | |
dc.date.issued | 2019-11-27 | |
dc.identifier.citation | García Fernández, E. et. al. Chem. Commun., 2019, 55, 14958. [https://doi.org/10.1039/C9CC08069D] | es_ES |
dc.identifier.uri | https://hdl.handle.net/10481/97955 | |
dc.description.abstract | A simple method for direct detection of microRNAs (miRs) in human
serum without the use of polymerase amplification is presented,
achieving low miR-122 concentrations and importantly, discerning
effectively single-base sequence mutations. The method is based
on the capture of target miRs with synthetic peptide nucleic acid
oligomers, dynamic chemical labelling, separation with quaternary
amine microplatforms and detection using time-gated fluorescence
imaging. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Royal Society of Chemistry | es_ES |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | miR-122 direct detection in human serum by time-gated fluorescence imaging | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.1039/C9CC08069D | |
dc.type.hasVersion | VoR | es_ES |