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dc.contributor.authorHernández Torres, Francisco 
dc.contributor.authorMatías Valiente, Lidia
dc.contributor.authorAlzas-Gomez, Virginia
dc.contributor.authorEva Aranega, Amelia
dc.date.accessioned2024-10-29T07:46:22Z
dc.date.available2024-10-29T07:46:22Z
dc.date.issued2024-09-27
dc.identifier.citationHernández Torres, F. et. al. Mol. Sci. 2024, 25, 10393. [https://doi.org/10.3390/ijms251910393]es_ES
dc.identifier.urihttps://hdl.handle.net/10481/96427
dc.description.abstractMacrophages are essential to muscle regeneration, as they regulate inflammation, carry out phagocytosis, and facilitate tissue repair. These cells exhibit phenotypic switching from proinflammatory (M1) to anti-inflammatory (M2) states during muscle repair, influencing myoblast proliferation, differentiation, and myofiber formation. In Duchenne Muscular Dystrophy (DMD), asynchronous muscle injuries disrupt the normal temporal stages of regeneration, leading to fibrosis and failed regeneration. Altered macrophage activity is associated with DMD progression and physiopathology. Gaining insight into the intricate relationship between macrophages and muscle cells is crucial for creating effective therapies aimed at treating this muscle disorder. This review explores the dynamic functions of macrophages in muscle regeneration and their implications in DMD.es_ES
dc.description.sponsorshipGrants DUCHENNE_2018/001 (Duchenne Parent Project, Spain Foundation)es_ES
dc.description.sponsorshipPID2022–138163OB-C31 (Ministerio de Ciencia e Innovación, Gobierno de España)es_ES
dc.description.sponsorshipProyExcel_00513 (Consejería de Universidad, Investigación e Innovación, Junta de Andalucía)es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectmacrophages es_ES
dc.subjectinflammationes_ES
dc.subjectskeletal musclees_ES
dc.titleMacrophages in the Context of Muscle Regeneration and Duchenne Muscular Dystrophyes_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.3390/ijms251910393
dc.type.hasVersionVoRes_ES


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Atribución 4.0 Internacional
Except where otherwise noted, this item's license is described as Atribución 4.0 Internacional