Flavor recognition memory related activity of the posterior piriform cortex in adult and aged rats
Metadatos
Afficher la notice complèteAuteur
Grau Perales, Alejandro Borja; Gómez Chacón, Beatriz; Morillas, Enrique; Gallo Torre, MilagrosEditorial
Elservier
Materia
Aging Flavor C-Fos Attenuation of neophobia Recognition memory Piriform cortex
Date
2019Patrocinador
This work was supported by the research projects PSI2014-57643-P, PSI2017-86381-P (MINECO. Spain) and FPU14/01531 (predoctoral fellowship to A.B. Grau-Perales (MECD, Spain)Résumé
The relationship between the piriform cortex and flavor recognition memory was investigated in adult and aged rats. By using c-Fos immunohistochemistry, we assessed the piriform cortex activity induced by flavor familiarity. The results indicated increased activity in the rostral region of the posterior piriform cortex elicited by the most familiar cider vinegar solution after six exposures. Aged rats exhibited overall increased activity in the posterior, but not the anterior piriform cortex, which was not related to flavor familiarity. This suggests that the posterior piriform cortex is related to flavor recognition memory and that aging modifies its activity pattern
which might underlie their slower attenuation of flavor neophobia.