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Levels of Bisphenol A and its analogs in nails, saliva, and urine of children: a case control study
dc.contributor.author | Gálvez Ontiveros, Yolanda | |
dc.contributor.author | Moscoso Ruiz, Inmaculada | |
dc.contributor.author | Almazán Fernández de Bobadilla, Laura | |
dc.contributor.author | Monteagudo Sánchez, Celia | |
dc.contributor.author | Rodrigo Conde Salazar, Lourdes T. | |
dc.contributor.author | Zafra Gómez, Alberto | |
dc.contributor.author | Rivas Velasco, Ana María | |
dc.date.accessioned | 2023-10-16T09:24:34Z | |
dc.date.available | 2023-10-16T09:24:34Z | |
dc.date.issued | 2023-08-14 | |
dc.identifier.citation | Gálvez-Ontiveros Y, Moscoso-Ruiz I, Almazán Fernández de Bobadilla V, Monteagudo C, Giménez-Martínez R, Rodrigo L, Zafra-Gómez A and Rivas A (2023) Levels of Bisphenol A and its analogs in nails, saliva, and urine of children: a case control study. Front. Nutr. 10:1226820. [doi: 10.3389/fnut.2023.1226820] | es_ES |
dc.identifier.uri | https://hdl.handle.net/10481/85015 | |
dc.description.abstract | Introduction: A growing number of studies link the increase in overweight/ obesity worldwide to exposure to certain environmental chemical pollutants that display obesogenic activity (obesogens). Since exposure to obesogens during the first stages of life has been shown to have a more intense and pronounced effect at lower doses, it is imperative to study their possible effects in childhood. The objective here was to study the association of Bisphenol A (BPA) and 11 BPA analogs in children, using three biological matrices (nails, saliva and urine), and overweight and obesity (n = 160). Methods: In this case–control study, 59 overweight/obese children and 101 controls were included. The measuring of Bisphenols in the matrices was carried out by ultra-high performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry (UHPLC-MS/MS). Logistic regression was used to study the association between overweight/obesity and Bisphenol exposure. Results: The results suggested that BPF in nails is associated with overweight/ obesity in children (OR:4.87; p = 0.020). In saliva, however, the highest detected concentrations of BPAF presented an inverse association (OR: 0.06; p = 0.010) with overweight/obesity. No associations of statistical significance were detected between exposure to BPA or its other analogs and overweight/obesity in any of the biological matrices. | es_ES |
dc.description.sponsorship | FEDER-Consejería de Salud y Familias’ of the Junta de Andalucía PE-0250-2019 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Frontiers | es_ES |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Overweight and obesity | es_ES |
dc.subject | Childhood obesity | es_ES |
dc.subject | Obesogens | es_ES |
dc.subject | BPA and analogs | es_ES |
dc.subject | Biological samples | es_ES |
dc.title | Levels of Bisphenol A and its analogs in nails, saliva, and urine of children: a case control study | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.3389/fnut.2023.1226820 | |
dc.type.hasVersion | VoR | es_ES |