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Cranial and extracranial giant cell arteritis do not exhibit differences in the IL6 -174 G/C gene polymorphism

dc.contributor.authorGenre, F.
dc.contributor.authorOrtego Centeno, Norberto 
dc.date.accessioned2023-10-03T10:36:16Z
dc.date.available2023-10-03T10:36:16Z
dc.date.issued2021-10-26
dc.identifier.citationPrieto-Peña, D., Remuzgo-Martínez, S., Atienza-Mateo, B. et al. Cranial and extracranial giant cell arteritis do not have different HLA-DRB1 and HLA-B association in Caucasian individuals. Arthritis Res Ther 23, 268 (2021). [https://doi.org/10.1186/s13075-021-02659-9]es_ES
dc.identifier.urihttps://hdl.handle.net/10481/84805
dc.description.abstractSince interleukin-6 (IL-6) is a pivotal proinflammatory cytokine implicated in the pathogenesis of giant cell arteritis (GCA), we aimed to determine the potential association of the functional IL6 -174 G/C polymorphism with GCA as well as if the single base change variation at the promoter region in the human IL-6 gene may account for differences in the clinical spectrum of GCA between cranial and extracranial large-vessel vasculitis (LVV)-GCA.es_ES
dc.description.sponsorshipInstituto de Salud Carlos III CM20/00006es_ES
dc.description.sponsorshipEuropean Union (EU)es_ES
dc.description.sponsorshipInstituto de Salud Carlos III Spanish Governmentes_ES
dc.description.sponsorshipMarie Curie Actions European Union (EU) RD16/0012/0014 PI17/00409es_ES
dc.description.sponsorshipResearch Executive Agency (REA) of the European Union 734899-Olive-Netes_ES
dc.description.sponsorshipInstituto de Salud Carlos III Spanish Governmentes_ES
dc.description.sponsorshipEuropean Social Fund (ESF) CP16/00033es_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectGiant cell arteritises_ES
dc.subjectLarge-vessel vasculitises_ES
dc.subjectIL6 -174 G/C (rs1800795)es_ES
dc.subjectPolymorphismes_ES
dc.titleCranial and extracranial giant cell arteritis do not exhibit differences in the IL6 -174 G/C gene polymorphismes_ES
dc.typejournal articlees_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/EU/RD16/0012/0014 PI17/00409es_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.1186/s13075-021-02659-9
dc.type.hasVersionVoRes_ES


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