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dc.contributor.authorRazola Díaz, María del Carmen 
dc.contributor.authorMontijo Prieto, Soumi de
dc.contributor.authorAznar Ramos, María José 
dc.contributor.authorJiménez Varela, María
dc.contributor.authorRuiz-Bravo López, Alfonso 
dc.contributor.authorVerardo, Vito 
dc.contributor.authorGómez Caravaca, Ana María 
dc.date.accessioned2023-07-19T09:15:12Z
dc.date.available2023-07-19T09:15:12Z
dc.date.issued2023-04-27
dc.identifier.citationRazola-Díaz, M.d.C.; De Montijo-Prieto, S.; Aznar-Ramos, M.J.; Jiménez-Valera, M.; Ruiz-Bravo, A.; Verardo, V.; Gómez-Caravaca, A.M. Effect of Lactic Acid Bacteria Fermentation on the Polar Compounds Content with Antioxidant and Antidiabetic Activity of Avocado Seed Extracts. Fermentation 2023, 9, 420. https://doi.org/10.3390/fermentation9050420es_ES
dc.identifier.urihttps://hdl.handle.net/10481/83864
dc.description.abstractAvocado seeds, a common waste in the avocado processing industry, have been found to have several bioactivities, such as anticancer, antimicrobial, hypocholesterolemic, antioxidant, and antidiabetic activities, among others. Nowadays, this wastage is causing an environmental problem, so the use of new technologies to take advantage of it is a novel field of research. In this study, the submerged fermentation by lactic acid bacteria was used as a novel tool for improving the bioactive compound extraction from avocado seeds. Avocado seeds were fermented by different strains, their polar compounds were identified and quantified by HPLC-ESI-TOF-MS, the antioxidant activity was measured by DPPH and FRAP assays, and the antidiabetic activity was analyzed by the alpha-amylase assay. A total of 32 polar compounds were identified, with 13 of them being described in avocado seeds for the first time. Avocado seeds fermented by Pentosaceus acidilactici showed the highest sum of polar compounds (6279.63 67.74 g/g d.w.), and by extension, of hydroxytyrosol glucoside (2989.76 3.64 g/g d.w.). Lactiplantibacillus plantarum CECT 9567 showed the highest antioxidant activity measured by both DPPH and FRAP assays (6294.67 19.44 and 6846.91 2.13 g TE/g d.w., respectively). Furthermore, Lactiplantibacillus plantarum CECT 748T had the highest antidiabetic activity (52.15% 0.67% inhibition of alpha-amylase activity), attributable to the polyphenols. According to the results, submerged fermentation by lactic acid bacteria led to an interesting increase of the polar compounds’ extractability of avocado seeds, consequently improving the bioactivities of the extracts, which could then be used for food nutraceutical or cosmetic purposes.es_ES
dc.description.sponsorshipProject RTI2018-099835-A-I00es_ES
dc.description.sponsorshipMCIN/AEI/ 10.13039/501100011033/FEDER, “Una manera de hacer Europaes_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAvocado seed wastees_ES
dc.subjectHPLC-ESI-TOF-MSes_ES
dc.subjectAlpha-amylasees_ES
dc.subjectSubmerged fermentationes_ES
dc.subjectPhenolic compoundses_ES
dc.titleEffect of Lactic Acid Bacteria Fermentation on the Polar Compounds Content with Antioxidant and Antidiabetic Activity of Avocado Seed Extractses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/fermentation9050420
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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Atribución 4.0 Internacional
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