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Compact Modeling of Two-Dimensional Field-Effect Biosensors
dc.contributor.author | Pasadas Cantos, Francisco | |
dc.contributor.author | El Grour, Tarek | |
dc.contributor.author | González Marín, Enrique | |
dc.contributor.author | Medina Rull, Alberto | |
dc.contributor.author | Toral López, Alejandro | |
dc.contributor.author | Cuesta López, Juan | |
dc.contributor.author | García Ruiz, Francisco Javier | |
dc.contributor.author | El Mir, Lassad | |
dc.contributor.author | Godoy Medina, Andrés | |
dc.date.accessioned | 2023-04-12T11:25:33Z | |
dc.date.available | 2023-04-12T11:25:33Z | |
dc.date.issued | 2023-02-07 | |
dc.identifier.citation | Pasadas, F.; El Grour, T.; G. Marin, E.; Medina-Rull, A.; Toral-Lopez, A.; Cuesta-Lopez, J.; G. Ruiz, F.; El Mir, L.; Godoy, A. Compact Modeling of Two-Dimensional Field-Effect Biosensors. Sensors 2023, 23, 1840. [https://doi.org/10.3390/s23041840] | es_ES |
dc.identifier.uri | https://hdl.handle.net/10481/81025 | |
dc.description.abstract | A compact model able to predict the electrical read-out of field-effect biosensors based on two-dimensional (2D) semiconductors is introduced. It comprises the analytical description of the electrostatics including the charge density in the 2D semiconductor, the site-binding modeling of the barrier oxide surface charge, and the Stern layer plus an ion-permeable membrane, all coupled with the carrier transport inside the biosensor and solved by making use of the Donnan potential inside the ion-permeable membrane formed by charged macromolecules. This electrostatics and transport description account for the main surface-related physical and chemical processes that impact the biosensor electrical performance, including the transport along the low-dimensional channel in the diffusive regime, electrolyte screening, and the impact of biological charges. The model is implemented in Verilog-A and can be employed on standard circuit design tools. The theoretical predictions obtained with the model are validated against measurements of a MoS2 field-effect biosensor for streptavidin detection showing excellent agreement in all operation regimes and leading the way for the circuit-level simulation of biosensors based on 2D semiconductors. | es_ES |
dc.description.sponsorship | Spanish Government MCIN/AEI/10.13039/501100011033 through the projects PID2020-116518GB-I00 and TED2021-129769B-I00 (MCIU/AEI/FEDER-UE) | es_ES |
dc.description.sponsorship | FEDER/Junta de Andalucía-Consejería de Transformacion Económica, Industria, Conocimiento y Universidades through the projects P20_00633 and A-TIC-646-UGR20 | es_ES |
dc.description.sponsorship | PAIDI 2020 and the European Social Fund Operational Programme 2014–2020 no. 208 | es_ES |
dc.description.sponsorship | MCIN/AEI/PTA grant, with reference PTA2020- 018250-I | es_ES |
dc.description.sponsorship | FPU program FPU019/05132 | es_ES |
dc.description.sponsorship | Plan Propio of Universidad de Granada | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | 2D | es_ES |
dc.subject | Biosensors | es_ES |
dc.subject | Field-effect transistor | es_ES |
dc.subject | Immunosensor | es_ES |
dc.subject | Modeling | es_ES |
dc.subject | MoS2 | es_ES |
dc.subject | Sensor | es_ES |
dc.subject | TMD | es_ES |
dc.subject | Two-dimensional | es_ES |
dc.subject | Verilog-A | es_ES |
dc.title | Compact Modeling of Two-Dimensional Field-Effect Biosensors | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.3390/s23041840 | |
dc.type.hasVersion | VoR | es_ES |