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dc.contributor.authorOrtiz Sandoval, Pilar 
dc.contributor.authorTorres Sánchez, Alfonso 
dc.contributor.authorLópez Moreno, Ana 
dc.contributor.authorCerk, Klara 
dc.contributor.authorRuiz Moreno, Ángel
dc.contributor.authorMonteoliva Sánchez, Mercedes 
dc.contributor.authorAmpatzoglou, Antonios 
dc.contributor.authorAguilera Gómez, Margarita 
dc.contributor.authorGruszecka-Kosowska, Agnieszka Malgorzata
dc.identifier.citationOrtiz, P... [et al.]. Impact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health. J. Xenobiot. 2022, 12, 56–63. []es_ES
dc.description.abstractChemical risk assessment in the context of the risk analysis framework was initially designed to evaluate the impact of hazardous substances or xenobiotics on human health. As the need of multiple stressors assessment was revealed to be more reliable regarding the occurrence and severity of the adverse effects in the exposed organisms, the cumulative risk assessment started to be the recommended approach. As toxicant mixtures and their “cocktail effects” are considered to be main hazards, the most important exposure for these xenobiotics would be of dietary and environmental origin. In fact, even a more holistic prism should currently be considered. In this sense, the definition of One Health refers to simultaneous actions for improving human, animal, and environmental health through transdisciplinary cooperation. Global policies necessitate going beyond the classical risk assessment for guaranteeing human health through actions and implementation of the One Health approach. In this context, a new perspective is proposed for the integration of microbiome biomarkers and next generation probiotics potentially impacting and modulating not only human health, but plant, animal health, and the environment.es_ES
dc.rightsAtribución 3.0 España*
dc.subjectRisk assessment es_ES
dc.subjectFarm to fork strategyes_ES
dc.subjectADME approaches_ES
dc.titleImpact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Healthes_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España