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dc.contributor.authorFernández Ochoa, Álvaro
dc.contributor.authorLeyva Jiménez, Francisco Javier
dc.contributor.authorCádiz Gurrea, María de la Luz 
dc.contributor.authorPimentel Moral, Sandra
dc.contributor.authorSegura Carretero, Antonio 
dc.date.accessioned2021-05-24T10:25:45Z
dc.date.available2021-05-24T10:25:45Z
dc.date.issued2021-03-22
dc.identifier.citationFernández-Ochoa, Á.; Leyva-Jiménez, F.J.; De la Luz Cádiz-Gurrea, M.; Pimentel-Moral, S.; Segura-Carretero, A. The Role of High-Resolution Analytical Techniques in the Development of Functional Foods. Int. J. Mol. Sci. 2021, 22, 3220. [https://doi.org/10.3390/ijms22063220]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/68676
dc.descriptionThis work was supported by the projects RTI2018-096724-B-C22 (Ministry of Science, Innovation and Universities) and P18-TP-3589 (Consejeria de Economia, Conocimiento, Empresas y Universidad from Junta de Andalucia). The author a Fernandez-Ochoa is grateful to the University of Granada for his post-doctoral contract ("Contrato Puente") during the years 2019-2020. The author FJ. Leyva-Jimenez received support from the Spanish Ministry of Economy and Competitiveness (MINECO) for the FPI grant BES-2016-076618 given to develop this work. The author M.d.l.L Cadiz-Gurrea is grateful to the Regional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusia for the contract for Young Researchers (PAIDI) at the University of Granada. S. Pimentel-Moral is also grateful to the University of Granada for her postdoctoral contract.es_ES
dc.description.abstractThe approaches based on high-resolution analytical techniques, such as nuclear magnetic resonance or mass spectrometry coupled to chromatographic techniques, have a determining role in several of the stages necessary for the development of functional foods. The analyses of botanical extracts rich in bioactive compounds is one of the fundamental steps in order to identify and quantify their phytochemical composition. However, the compounds characterized in the extracts are not always responsible for the bioactive properties because they generally undergo metabolic reactions before reaching the therapeutic targets. For this reason, analytical techniques are also applied to analyze biological samples to know the bioavailability, pharmacokinetics and/or metabolism of the compounds ingested by animal or human models in nutritional intervention studies. In addition, these studies have also been applied to determine changes of endogenous metabolites caused by prolonged intake of compounds with bioactive potential. This review aims to describe the main types and modes of application of high-resolution analytical techniques in all these steps for functional food development.es_ES
dc.description.sponsorshipMinistry of Science, Innovation and Universities RTI2018-096724-B-C22es_ES
dc.description.sponsorshipJunta de Andalucia P18-TP-3589es_ES
dc.description.sponsorshipSpanish Ministry of Economy and Competitiveness (MINECO) BES-2016-076618es_ES
dc.description.sponsorshipRegional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusiaes_ES
dc.description.sponsorshipUniversity of Granadaes_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectAnalytical techniqueses_ES
dc.subjectAnalytical chemistryes_ES
dc.subjectChromatographyes_ES
dc.subjectFunctional foods es_ES
dc.subjectMass spectrometry es_ES
dc.subjectNuclear magnetic resonance es_ES
dc.subjectMetabolomicses_ES
dc.subjectPhytochemicals es_ES
dc.titleThe Role of High-Resolution Analytical Techniques in the Development of Functional Foodses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/ijms22063220
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España