Role of Vitamin D in the Metabolic Syndrome
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AuthorMelguizo Rodríguez, Lucía Raquel; Costela Ruiz, Víctor Javier; García Recio, Enrique; Luna Bertos, María Elvira De; Ruiz Rodríguez, Concepción; Illescas Montes, Rebeca
Metabolic syndromeVitamin DCardiovascular riskDiabetes MellitusObesityInsulin resistance
Melguizo-Rodríguez, L.; Costela-Ruiz, V.J.; García-Recio, E.; De Luna-Bertos, E.; Ruiz, C.; Illescas-Montes, R. Role of Vitamin D in the Metabolic Syndrome. Nutrients 2021, 13, 830. [https://doi.org/10.3390/nu13030830]
SponsorshipJunta de Andalucia; Department of Nursing (University of Granada)
The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS.