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Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients
dc.contributor.author | Nestares Pleguezuelo, María Teresa | |
dc.contributor.author | De la Flor Alemany, Marta | |
dc.contributor.author | Bonavita, Antonela | |
dc.contributor.author | Aparicio García-Molina, Virginia | |
dc.date.accessioned | 2021-03-04T09:15:19Z | |
dc.date.available | 2021-03-04T09:15:19Z | |
dc.date.issued | 2021-01-06 | |
dc.identifier.citation | Nestares, T.; Martín-Masot, R.; Flor-Alemany, M.; Bonavita, A.; Maldonado, J.; Aparicio, V.A. Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients. Nutrients 2021, 13, 156. [https://doi.org/10.3390/nu13010156] | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/66865 | |
dc.description.abstract | The current study was designed to assess the influence of consumption of ultra-processed (UPF) on oxidative/antioxidant balance and evoked inflammatory signaling in young patients with celiac disease (CD). The study included 85 children. The celiac group (n = 53) included children with CD with a long (>18 months, n = 17) or recent (<18 months, n = 36) adherence to a gluten-free diet (GFD). The control group (n = 32) included healthy children with a significantly lower consumption of UPF compared to the CD group, both expressed as kcal/day (p = 0.043) and as percentage of daily energy intake (p = 0.023). Among children with CD, the group with the lowest consumption of UPF (below the 50% of daily energy intake) had a greater Mediterranean diet (MD) adherence and higher moderate physical activity levels. In addition, CD children with the lowest consumption of UPF had healthier redox (lower soluble superoxide dismutase-1 and 15-F2t-isoprostanes) and inflammatory profiles (lower macrophage inflammatory protein-1 ) compared to the group with the highest consumption of UPF (all, p < 0.05) regardless of the time on a GFD. These findings highlight the importance of a correct monitoring of the GFD. An unbalanced GFD with high consumption of UPF and an unhealthy pattern with less physical activity and worse adherence to MD results in a worse inflammatory profile, which could act as a parallel pathway that could have important consequences on the pathophysiology of the disease. | es_ES |
dc.description.sponsorship | Regional Government of Andalusia, Excellence Research Project P12-AGR-2581 | es_ES |
dc.description.sponsorship | University of Granada PP2017-PIP14 | es_ES |
dc.description.sponsorship | Spanish Ministry of Education, Culture and Sports FPU17/03715 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Mdpi | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | Celiac disease | es_ES |
dc.subject | Ultra-processed foods | es_ES |
dc.subject | Gluten-free diet | es_ES |
dc.subject | Inflammatory signaling | es_ES |
dc.subject | Oxidative stress | es_ES |
dc.subject | Children | es_ES |
dc.title | Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.3390/nu13010156 | |
dc.type.hasVersion | VoR | es_ES |