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dc.contributor.authorNieto, Daniel
dc.contributor.authorMarchal Corrales, Juan Antonio 
dc.contributor.authorJorge de Mora, Alberto
dc.contributor.authorMoroni, Lorenzo
dc.identifier.citationNieto, Daniel Marchal Corrales, Juan Antonio Jorge de Mora, Alberto Moroni, Lorenzo. Fundamentals of light-cell–polymer interactions in photo-cross-linking based bioprinting. APL Bioengineering 4, 041502 (2020); []es_ES
dc.descriptionDATA AVAILABILITY The data that support the findings of this study are available within the article.es_ES
dc.descriptionDaniel Nieto thanks the support from the Xunta de Galicia, Spain, under the Galician Programme for Research Innovation and Growth 2011-2015 (I2C Plan). Lorenzo Moroni is grateful to the Dutch Province of Limburg and to the European Research Council starting grant “Cell Hybridge” (Grant No. 637308). This work was supported by Consejería de Economía, Conocimiento, Empresas y Universidad de la Junta de Andalucía and European Regional Development Funds (ERDF) (Project Nos. B-CTS-230-UGR18 and PY18–2470) and the Instituto de Salud Carlos III, ERDF funds (No. DTS19/00145).es_ES
dc.description.abstractBiofabrication technologies that use light for polymerization of biomaterials have made significant progress in the quality, resolution, and generation of precise complex tissue structures. In recent years, the evolution of these technologies has been growing along with the development of new photocurable resins and photoinitiators that are biocompatible and biodegradable with bioactive properties. Such evolution has allowed the progress of a large number of tissue engineering applications. Flexibility in the design, scale, and resolution and wide applicability of technologies are strongly dependent on the understanding of the biophysics involved in the biofabrication process. In particular, understanding cell–light interactions is crucial when bioprinting using cell-laden biomaterials. Here, we summarize some theoretical mechanisms, which condition cell response during bioprinting using light based technologies. We take a brief look at the light–biomaterial interaction for a better understanding of how linear effects (refraction, reflection, absorption, emission, and scattering) and nonlinear effects (two-photon absorption) influence the biofabricated tissue structures and identify the different parameters essential for maintaining cell viability during and after bioprinting.es_ES
dc.description.sponsorshipXunta de Galiciaes_ES
dc.description.sponsorshipEuropean Research Council starting grant "Cell Hybridge" 637308es_ES
dc.description.sponsorshipJunta de Andaluciaes_ES
dc.description.sponsorshipEuropean Union (EU) B-CTS-230-UGR18 PY18-2470es_ES
dc.description.sponsorshipInstituto de Salud Carlos III, ERDF funds DTS19/00145es_ES
dc.publisherAmerican Institute of Physicses_ES
dc.rightsAtribución 3.0 España*
dc.titleFundamentals of light-cell–polymer interactions in photo-cross-linking based bioprintinges_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/Cell Hybridge 637308es_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España