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A quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMR

dc.contributor.authorMedina Carmona, Encarnación 
dc.date.accessioned2020-11-06T12:17:50Z
dc.date.available2020-11-06T12:17:50Z
dc.date.issued2020-10-07
dc.identifier.citationMedina-Carmona, E., Varela, L., Hendry, A. C., Thompson, G. S., White, L. J., Boles, J. E., ... & Ortega-Roldan, J. L. (2020). A quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMR. Chemical Communications, 56(78), 11665-11668.[DOI: 10.1039/d0cc03612a]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/64106
dc.description.abstractThe activity of membrane proteins and compounds that interact with the membrane is modulated by the surrounding lipid composition. However, there are no simple methods that determine the composition of these annular phospholipids in eukaryotic systems. Herein, we describe a simple methodology that enables the identification and quantification of the lipid composition around membrane-associated compounds using SMA-nanodiscs and routine 1H–31P NMR.es_ES
dc.description.sponsorshipWellcome Trust 207743/Z/17/Zes_ES
dc.description.sponsorshipRoyal Society of London RGS\R1\191414es_ES
dc.description.sponsorshipPublic Health Englandes_ES
dc.language.isoenges_ES
dc.publisherRoyal Society Chemistryes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.rightsAtribución-NoComercial 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.subjectMaleic Acid Copolymeres_ES
dc.subjectModulationes_ES
dc.subjectBilayeres_ES
dc.subjectInsertses_ES
dc.subjectChanneles_ES
dc.titleA quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMRes_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.1039/d0cc03612a
dc.type.hasVersionVoRes_ES


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