Functional Ingredients based on Nutritional Phenolics. A Case Study against Inflammation: Lippia Genus
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AuthorLeyva Jiménez, Francisco Javier; Lozano Sánchez, Jesús; Cádiz-Gurrea, María de la Luz; Arráez Román, David; Segura Carretero, Antonio
Phenolic compoundsAnti-inflammatoryPro-inflammatory mediatorsCytokinesProstaglandins
Leyva-Jiménez, F. J., Lozano-Sánchez, J., Cádiz-Gurrea, M. D. L. L., Arráez-Román, D., & Segura-Carretero, A. (2019). Functional Ingredients based on Nutritional Phenolics. A Case Study against Inflammation: Lippia Genus. Nutrients, 11(7), 1646.
SponsorshipThis work was funded by projects AGL2015-67995-C3-2-R and IJCI2015-26789 (Spanish Ministry of Science and Innovation), P11-CTS-7625 (Andalusian Regional Government Council of Innovation and Science) and RTI2018-096724-B-C22 (Ministry of Science, Innovation and Universities). The author Leyva-Jimenez gratefully acknowledges the Spanish Ministry of Economy and Competitiveness (MINECO) for the FPI grant BES-2016-076618 given to develop this work.
Epidemiological studies have reported convincing evidence that natural dietary compounds may modify inflammation, it being an important event described in the pathophysiology of age-related infirmity. Among different dietary components, nutritional phenolics have demonstrated links to a lower risk of inflammation in the most common degenerative and chronic diseases. In this way, the healthy potential of phenolics against inflammation and the emergence of new functional ingredients have caused an enhancement of nutraceutical and functional food formulation. The present review focuses on: (a) nutritional phenolics and their effects on inflammation and (b) functional ingredients based on phenolic compounds with anti-inflammatory properties. Furthermore, the emerging interest in health-promoting products by consumers has caused an increase in the demand for functional products and nutraceuticals. Additionally, this review includes a case study of the Lippia genus, which has shown anti-inflammatory effects claiming to be a natural alternative for the management of this physiological disorder. This report is a practical tool for healthcare providers.