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dc.contributor.authorMartín-García, Beatriz
dc.contributor.authorPasini, Federica
dc.contributor.authorVerardo, Vito 
dc.contributor.authorDíaz-de-Cerio, Elixabet
dc.contributor.authorTylewicz, Urszula
dc.contributor.authorGómez Caravaca, Ana María 
dc.contributor.authorCaboni, Maria Fiorenza
dc.date.accessioned2020-04-15T11:45:35Z
dc.date.available2020-04-15T11:45:35Z
dc.date.issued2019-08-06
dc.identifier.citationMartín-García, B., Pasini, F., Verardo, V., Díaz-de-Cerio, E., Tylewicz, U., Gómez-Caravaca, A. M., & Caboni, M. F. (2019). Optimization of sonotrode ultrasonic-assisted extraction of proanthocyanidins from brewers’ spent grains. Antioxidants, 8(8), 282.es_ES
dc.identifier.urihttp://hdl.handle.net/10481/61252
dc.description.abstractBrewing spent grains (BSGs) are the main by-product from breweries and they are rich of proanthocyanidins, among other phenolic compounds. However, literature on these compounds in BSGs is scarce. Thus, this research focuses on the establishment of ultrasound-assisted extraction of proanthocyanidin compounds in brewing spent grains using a sonotrode. To set the sonotrode extraction up, response surface methodology (RSM) was used to study the effects of three factors, namely, solvent composition, time of extraction, and ultrasound power. Qualitative and quantitative analyses of proanthocyanidin compounds were performed using HPLC coupled to fluorometric and mass spectrometer detectors. The highest content of proanthocyanidins was obtained using 80/20 acetone/water (v/v), 55 min, and 400W. The established method allows the extraction of 1.01 mg/g dry weight (d.w.) of pronthocyanidins from BSGs; this value is more than two times higher than conventional extraction.es_ES
dc.description.sponsorshipThis project was supported by the University of Granada (project PPJI2017.16).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectBox-Behnken Designes_ES
dc.subjectBrewers’ spent grainses_ES
dc.subjectProanthocyanidinses_ES
dc.subjectSonotrode ultrasonic-assisted extractiones_ES
dc.titleOptimization of Sonotrode Ultrasonic-Assisted Extraction of Proanthocyanidins from Brewers’ Spent Grainses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/antiox8080282


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Atribución 3.0 España
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