Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study
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Pérez Burillo, Sergio; Pastoriza de la Cueva, Silvia; Gironés, A.; Avellaneda, A.; Francino, M. Pilar; Rufián Henares, José ÁngelEditorial
Elsevier Ltd
Materia
Salami Citrus fiber Antioxidant capacity Short chain fatty acids Gut microbiota
Date
2020-01-21Referencia bibliográfica
Pérez-Burillo, S., Pastoriza, S., Gironés, A., Avellaneda, A., Francino, M. P., & Rufián-Henares, J. A. (2020). Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study. Journal of Functional Foods, 66, 103790.
Sponsorship
This trial was supported by project AVANZA-S from the Spanish Centre for the Development of Industrial Technology (CDTI). It was also supported by a Spanish predoctoral fellowship F.P.U. (ref.: FPU14/ 01192) for S. Perez-Burillo from the Spanish GovernmentAbstract
A human intervention in 24 healthy volunteers was performed to test the potential health benefits of a fermented
salami with a probiotic Lactobacillus rhamnosus HN001 and added citrus fiber. Anthropometric measurements
and blood biochemistry did not show any significant differences between pre- and post-intervention during
4 weeks with a daily intake of 30 g of salami, neither with regular salami (control group) nor with reformulated
salami (intervention group). However, the inflammatory markers CRP and TNFα decreased significantly after
intervention, suggesting a less inflammatory environment after reformulated salami consumption. Antioxidant
plasmatic markers also improved within the intervention group. Butyrate production was significantly increased
after reformulated salami consumption. Gut microbiota community structure, however, was not significantly
shaped by neither regular nor reformulated salami. After the intervention with probiotic salami, L. rhamnosus
was detected by quantitative polymerase chain reaction (qPCR) in all samples of the intervention group but not
in the control group, showing probiotic effect.