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dc.contributor.authorCorrea-Rodríguez, María
dc.contributor.authorPocovi-Gerardino, Gabriela
dc.contributor.authorCallejas-Rubio, José Luis
dc.contributor.authorRíos Fernández, Raquel
dc.contributor.authorMartín-Amada, María
dc.contributor.authorCruz-Caparros, María-Gracia
dc.contributor.authorOrtego-Centeno, Norberto
dc.contributor.authorRueda Medina, Blanca
dc.date.accessioned2019-05-18T21:15:46Z
dc.date.available2019-05-18T21:15:46Z
dc.date.issued2019-03-16
dc.identifier.citationCorrea-Rodríguez, M. [et al.]. Prognostic Nutritional Index and Nutritional Risk Index Are Associated with Disease Activity in Patients with Systemic Lupus Erythematosus. Nutrients 2019, 11, 638; doi:10.3390/nu11030638.es_ES
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10481/55762
dc.description.abstractThe prognostic nutritional index (PNI), controlling nutritional status (CONUT) score and nutritional risk index (NRI) have been described as useful screening tools for patient prognosis in several diseases. The aim of this study was to examine the relationship between PNI, CONUT and NRI with clinical disease activity and damage in 173 patients with systemic lupus erythematous (SLE). Disease activity was assessed with the SLE disease activity index (SLEDAI-2K), and disease-related organ damage was assessed using the SLICC/ACR damage index (SDI) damage index. PNI and NRI were significantly lower in active SLE patients than in inactive SLE patients (p < 0.001 and p = 0.012, respectively). PNI was inversely correlated with the SLEDAI score (p < 0.001) and NRI positively correlated with SLEDAI and SDI scores (p = 0.027 and p < 0.001). Linear regression analysis adjusting for age, sex and medications showed that PNI was inversely correlated with SLEDAI ( (95% CI) = -0.176 (-0.254, -0.098), p < 0.001) and NRI positively correlated with SLEDAI ( (95% CI) = 0.056 (0.019, 0.093), p = 0.003) and SDI ( (95% CI) = 0.047 (0.031, 0.063), p < 0.001). PNI (odds ratio (OR) 0.884, 95% confidence interval (CI) 0.809–0.967, p = 0.007) and NRI ((OR) 1.067, 95% CI 1.028–1.108, p = 0.001) were independent predictors of active SLE. These findings suggest that PNI and NRI may be useful markers to identify active SLE in clinical practice.es_ES
dc.description.sponsorshipThis study was supported by the grant PI0523-2016 from “Consejería de igualdad, salud y políticas sociales” (Junta de Andalucía) and is part of the research group LyDIMED “Lupus y Dieta Mediterránea”. G. Pocovi-Gerardino is a predoctoral fellow from the doctoral program “Medicina clínica y salud pública” of the University of Granadaes_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectPrognostic nutritional indexes_ES
dc.subjectControlling nutritional statuses_ES
dc.subjectNutritional risk indexes_ES
dc.subjectSystemic lupus erythematosus es_ES
dc.subjectLupus disease activityes_ES
dc.subjectLupus damagees_ES
dc.titleThe Prognostic Nutritional Index and Nutritional Risk Index Are Associated with Disease Activity in Patients with Systemic Lupus Erythematosuses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/nu11030638


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