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dc.contributor.authorMykhailenko, Olgaes_ES
dc.contributor.authorKovalyov, Volodumures_ES
dc.contributor.authorKovalyov, Sergiyes_ES
dc.contributor.authorKrechun, Anastasiiaes_ES
dc.identifier.citationMykhailenko, O.; et al. Isoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extract. Ars Pharm, 58(1): 39-45 (2017). []es_ES
dc.descriptionThe authors would like gratitude to acting as a Head of the Laboratory of Biochemistry of Microorganisms and Nutrient Media of the State Institution “Institute of Microbiology and Immunology named after I.I. Mechnikov of the National Academy of Medical Sciences of Ukraine,” Cand. Med. Sci. T.P. Osolodchenko for the preliminary screening of antimicrobial activities and a Head of Department of the Ornamental plants, Senior Researcher of the National Botanical Garden n.a. M.M. Gryshko of NAS of Ukraine (Kyiv), Cand. Biol. Sci. Yu.V. Buidin for help in systematical classification of plants.en_EN
dc.description.abstractAim: The aim of the work was isolation and identification of the phenolic compounds from the rhizomes of Iris hungarica. Materials and methods: To establish by chemical and spectral methods for the structures of phenolic compounds, which were isolated from the rhizomes of Iris hungarica Waldst. et Kit. (Iridaceae family). Compounds were obtained by column chromatography on silica gel and their structures were determined by UV, IR, MS, 1H-NMR spectra methods. Preliminary screening of antibacterial activity was determined. Results: From the ethanolic extract of the rhizomes of I. hungarica, which is widespread in Ukraine, for the first time two new for this species isoflavones, teсtorigenin and tectoridin and xanthone mangiferin, together with known isoflavonoids daidzein, genistein, formononetin were isolated. The dry extract of the rhizomes of I. hungarica at a concentration of 1% has shown the highest inhibitory activity for Gram-positive bacteria and fungi.en_EN
dc.description.abstractObjetivo: El objetivo del trabajo es el aislamiento y la identificación de los compuestos fenólicos de los rizomas de Iris hungarica. Materiales y métodos: Se utilizaron métodos químicos y espectrales para conocer las estructuras de compuestos fenólicos que se aislaron de los rizomas de Iris hungarica Waldst. et Kit. (Familia de Iridaceae). Los compuestos se obtuvieron mediante cromatografía en columna sobre gel de sílice y se determinaron sus estructuras mediante análisis de sus espectros por UV, IR, MS, 1H-RMN. Se determinó el cribado preliminar de la actividad antibacteriana. Resultados: Se aislaron por primera vez de los rizomas de Iris hungarica (común en Ucrania) dos isoflavonas, teсtorigenina y tectoridina (nuevas para esta especie), el xantonoide mangiferina y los isoflavonoides daidzeina, genisteina y formononetina. El extracto seco de los rizomas de I. hungarica a una concentración de 1% ha mostrado la actividad inhibitoria más alta para bacterias y hongos Gram-positivos.es_ES
dc.publisherUniversidad de Granada. Facultad de Farmaciaes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licenseen_EN
dc.subjectIris hungaricaen_EN
dc.subjectAntibacterial activityen_EN
dc.subjectIris hungaricaes_ES
dc.subjectActividad antibacterianaes_ES
dc.titleIsoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extracten_EN
dc.title.alternativeIsoflavonoides de los rizomas de Iris hungarica y actividad antibacteriana del extracto de rizomas secoes_ES

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