Influence of the Chirality of Short Peptide Supramolecular Hydrogels in Protein Crystallogenesis

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URI: http://hdl.handle.net/10481/38532
ISSN: 1364-548X
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Author
Conejero-Muriel, Mayte; Gavira Gallardo, José Antonio; Pineda-Molina, Estela; Belsom, Adam; Bradley, Mark; Moral, Mónica; García López-Durán, Juan De Dios; Luque González, Angélica; Díaz Mochón, Juan José; Contreras-Montoya, Rafael; Martínez-Peragón, Ángela; Cuerva Carvajal, Juan Manuel; Álvarez Cienfuegos Rodríguez, Luis
Editorial
Royal Society of Chemistry
Materia
Hydrogel
 
Peptide
 
Date
2015
Referencia bibliográfica
Conejero-Muriel, M.; et al. Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis. Chemical Communications, 51: 3862-3865 (2015). [http://hdl.handle.net/10481/38532]
Sponsorship
MICINN (Spain) projects BIO2010-16800 (JAG), CTQ-2011.22455 (LAC & JMC), CTQ2012-34778 (JJDM & ALG), “Factoría Española de Cristalización” Consolider-Ingenio 2010 (JAG & MCM) and EDRF Funds (JAG, LAC & JMC), P12-FQM-2721 (LAC) Junta de Andalucía.; MINECO,Project No. FIS2013-41821-R.
Abstract
For the first time the influence of the chirality of the gel fibers in protein crystallogenesis has been studied. Enantiomeric hydrogels 1 and 2 were tested with model proteins lysozyme and glucose isomerase and a formamidase from B. cereus. Crystallization behaviour and crystal quality of these proteins in both hydrogels are presented and compared.
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