Influence of the Chirality of Short Peptide Supramolecular Hydrogels in Protein Crystallogenesis

Conejero-Muriel, Mayte; Gavira Gallardo, José Antonio; Pineda-Molina, Estela; Belsom, Adam; Bradley, Mark; Moral, Mónica; García López-Durán, Juan De Dios; Luque González, Angélica; Díaz Mochón, Juan José; Contreras-Montoya, Rafael; Martínez-Peragón, Ángela; Cuerva Carvajal, Juan Manuel; Álvarez Cienfuegos Rodríguez, Luis

doi:10.1039/C4CC09024A

ConejeroMuriel_Hydrogels_Crystallogenesis.pdf (265.7Kb)

Identificadores

URI: http://hdl.handle.net/10481/38532

DOI: 10.1039/C4CC09024A

ISSN: 1364-548X

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Editorial

Royal Society of Chemistry

Materia

Hydrogel

Peptide

Fecha

2015

Referencia bibliográfica

Conejero-Muriel, M.; et al. Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis. Chemical Communications, 51: 3862-3865 (2015). [http://hdl.handle.net/10481/38532]

Patrocinador

MICINN (Spain) projects BIO2010-16800 (JAG), CTQ-2011.22455 (LAC & JMC), CTQ2012-34778 (JJDM & ALG), “Factoría Española de Cristalización” Consolider-Ingenio 2010 (JAG & MCM) and EDRF Funds (JAG, LAC & JMC), P12-FQM-2721 (LAC) Junta de Andalucía.; MINECO,Project No. FIS2013-41821-R.

Resumen

For the first time the influence of the chirality of the gel fibers in protein crystallogenesis has been studied. Enantiomeric hydrogels 1 and 2 were tested with model proteins lysozyme and glucose isomerase and a formamidase from B. cereus. Crystallization behaviour and crystal quality of these proteins in both hydrogels are presented and compared.

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FQM144 - Artículos

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