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dc.contributor.authorGutiérrez-Fernández, José
dc.contributor.authorLuna Del Castillo, Juan De Dios 
dc.contributor.authorMañanes-González, Sara
dc.contributor.authorCarrillo-Ávila, José Antonio
dc.contributor.authorGutiérrez, Blanca
dc.contributor.authorCervilla, Jorge A.
dc.contributor.authorSorlozano Puerto, Antonio 
dc.date.accessioned2015-04-17T10:56:23Z
dc.date.available2015-04-17T10:56:23Z
dc.date.issued2015
dc.identifier.citationGutiérrez-Fernández, J.; et al. Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study. Neuropsychiatric Disease and Treatment, 11: 843-852 (2015). [http://hdl.handle.net/10481/35709]es_ES
dc.identifier.issn1178-2021
dc.identifier.urihttp://hdl.handle.net/10481/35709
dc.description.abstractIn the present study we have performed both a meta-analysis and an analytical study exploring the presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii antibodies in a sample of 143 schizophrenic patients and 143 control subjects. The meta-analysis was performed on papers published up to April 2014. The presence of serum immunoglobulin G and immunoglobulin A was performed by enzyme-linked immunosorbent assay test. The detection of microbial DNA in total peripheral blood was performed by nested polymerase chain reaction. The meta-analysis showed that: 1) C. pneumoniae DNA in blood and brain are more common in schizophrenic patients; 2) there is association with parasitism by T. gondii, despite the existence of publication bias; and 3) herpes viruses were not more common in schizophrenic patients. In our sample only anti-Toxoplasma immunoglobulin G was more prevalent and may be a risk factor related to schizophrenia, with potential value for prevention.es_ES
dc.description.sponsorshipPart of this work was presented at the Royal Academy of Medicine of Spain.es_ES
dc.language.isoenges_ES
dc.publisherDove Presses_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 License
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subjectMeta-analysises_ES
dc.subjectAnalytical studyes_ES
dc.subjectChlamydia pneumoniaees_ES
dc.subjectHerpes simplex virus type 1es_ES
dc.subjectHuman herpes virus 6es_ES
dc.subjectToxoplasma gondiies_ES
dc.subjectSchizophrenia es_ES
dc.titleDifferent presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.2147/NDT.S79285


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