SWI/SNF proteins as targets in cancer therapy

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URI: http://hdl.handle.net/10481/34955
ISSN: 1756-8722
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Autor
Schiaffino-Ortega, Santiago; Balinas, Carlos; Cuadros Celorrio, Marta Eugenia; Medina Vico, Pedro Pablo
Editorial
Biomed Central
Materia
SWI/SNF complex
 
Cancer therapy
 
Epigenetic
 
Tumor suppressor
 
Synthetic lethality
 
Leukemia
 
Lung cancer
 
BRG1
 
SMARCA4
 
BRM
 
SMARCA2
 
MAX
 
MYC
 
Fecha
2014
Referencia bibliográfica
Schiaffino-Ortega, S.; et al. SWI/SNF proteins as targets in cancer therapy. Journal of Hematology and Oncology, 7: 81 (2014). [http://hdl.handle.net/10481/34955]
Patrocinador
P.P.M. laboratory is funded by Ministry of Economy of Spain (SAF-2012- 37252), Junta de Andalucía (CICE-FEDER-BIO-1655, PeS-FEDER-PI-0903-2012), EU-MarieCurie (CIG-321926), CEI-BIOTIC (20 F12.6), Deutsche Leukämie-Stiftung and BBVA Foundation. P.P.M is a Ramon y Cajal Researcher (RYC-2011-07766). S S-O has a postdoctoral fellowship of Junta de Andalucía (CTS 03210) and the support of the CEI-BIOTIC (2014-MPBS33).
Resumen
Recent identification of synthetic lethal interactions involving several proteins of the SWI/SNF complex discussed in this Research Highlight has opened the possibility of new cancer therapeutic approaches.
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