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dc.contributor.authorLópez Jaramillo, Francisco Javier 
dc.contributor.authorHernández Mateo, Fernando 
dc.contributor.authorSantoyo González, Francisco
dc.identifier.citationLópez Jaramillo, F.J.; Hernández Mateo, F.; Santoyo González, F. Vinyl sulfone: a multi-purpose function in proteomics. In: Eastwood Leung, H.-C. (ed.), Integrative proteomics. Rijeka (Croatia): Intech, 2012. pp. 301- 326. []es_ES
dc.identifier.otherdoi: 10.5772/29682
dc.description.abstractThe chapter is organized in three sections. In a first instance, a general overview of the vinyl sulfone chemistry in terms of the most relevant methods of synthesis and aspects of their reactivity will be followed by a discussion of the application of this chemical behaviour with proteins. Their advantages and disadvantages with other currently available methodologies to modify amine and thiol groups naturally present in proteins will be compared. In a second section the applications of vinyl sulfones to Proteomics will be enumerated. Finally, the wide scope of the vinyl sulfone chemistry in other omic sciences will be discussed.es_ES
dc.description.sponsorshipThe authors acknowledge Dirección General de Investigación Científica y Técnica (DGICYT) (CTQ2008-01754) and Junta de Andalucía (P07-FQM-02899) for financial support.es_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.subjectVinyl sulfonees_ES
dc.subjectSynthesis es_ES
dc.titleVinyl sulfone: a multi-purpose function in proteomicses_ES

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