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Targeted retroviral infection of tumor cells by receptor co-operation
dc.contributor.author | Martin, Francisco | |
dc.contributor.author | Chowdhury, Simon | |
dc.contributor.author | Neil, Stuart | |
dc.contributor.author | chester, k | |
dc.contributor.author | Cosset, Francois | |
dc.contributor.author | collins, mary | |
dc.date.accessioned | 2025-01-31T08:31:20Z | |
dc.date.available | 2025-01-31T08:31:20Z | |
dc.date.issued | 2003 | |
dc.identifier.citation | Journal of Virology. Vol 77(4); Págs: 2753-2756 (2003) | es_ES |
dc.identifier.uri | https://hdl.handle.net/10481/101488 | |
dc.description.abstract | Retroviruses expressing two different receptor-binding domains linked by proline-rich spacers infect only cells expressing both retroviral receptors (Valsesia-Wittman et al., EMBO J. 6:1214-1223, 1997). Here we apply this receptor cooperation strategy to target human tumor cells by linking single-chain antibodies recognizing tumor antigens via proline-rich spacers to the 4070A murine leukemia virus surface protein. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | AMERICAN SOCIETY OF MICROBIOLOGY | es_ES |
dc.subject | targeting | es_ES |
dc.subject | gene therapy | es_ES |
dc.subject | tumor cells | es_ES |
dc.subject | receptor cooperation | es_ES |
dc.subject | envelope | es_ES |
dc.title | Targeted retroviral infection of tumor cells by receptor co-operation | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.1128/jvi.77.4.2753-2756.2003 | |
dc.type.hasVersion | AO | es_ES |