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dc.contributor.authorLozano Sánchez, Jesús es_ES
dc.contributor.authorCastro-Puyana, Maríaes_ES
dc.contributor.authorMendiola, José A.es_ES
dc.contributor.authorSegura Carretero, Antonio es_ES
dc.contributor.authorCifuentes, Alejandroes_ES
dc.contributor.authorIbáez, Elenaes_ES
dc.date.accessioned2017-02-23T10:50:33Z
dc.date.available2017-02-23T10:50:33Z
dc.date.issued2014
dc.identifier.citationLozano Sánchez, J.; et. al. Recovering Bioactive Compounds from Olive Oil Filter Cake by Advanced Extraction Techniques. International Journal Molecular Sciences, 15: 16270-16283 (2014). [http://hdl.handle.net/10481/45015]es_ES
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/10481/45015
dc.description.abstractThe potential of by-products generated during extra-virgin olive oil (EVOO) filtration as a natural source of phenolic compounds (with demonstrated bioactivity) has been evaluated using pressurized liquid extraction (PLE) and considering mixtures of two GRAS (generally recognized as safe) solvents (ethanol and water) at temperatures ranging from 40 to 175 °C. The extracts were characterized by high-performance liquid chromatography (HPLC) coupled to diode array detection (DAD) and electrospray time-of-flight mass spectrometry (HPLC-DAD-ESI-TOF/MS) to determine the phenolic-composition of the filter cake. The best isolation procedure to extract the phenolic fraction from the filter cake was accomplished using ethanol and water (50:50, v/v) at 120 °C. The main phenolic compounds identified in the samples were characterized as phenolic alcohols or derivatives (hydroxytyrosol and its oxidation product), secoiridoids (decarboxymethylated and hydroxylated forms of oleuropein and ligstroside aglycones), flavones (luteolin and apigenin) and elenolic acid derivatives. The PLE extraction process can be applied to produce enriched extracts with applications as bioactive food ingredients, as well as nutraceuticals.en_EN
dc.language.isospaes_ES
dc.publisherMDPIes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es_ES
dc.subjectOlive oil by-productsen_EN
dc.subjectFilter cakeen_EN
dc.subjectPhenolic compoundsen_EN
dc.subjectPressurized liquid extrationen_EN
dc.subjectHPLC-ESI-TOF/MISen_EN
dc.subjectGRAS solventsen_EN
dc.titleRecovering Bioactive Compounds from Olive Oil Filter Cake by Advanced Extraction Techniquesen_EN
dc.typejournal articleen_EN
dc.rights.accessRightsopen accessen_EN


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