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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/32451

Title: Antigen Incorporation on Cryptosporidium parvum Oocyst Walls
Authors: Entrala Torres, Emilio
Sbihi, Younes
Sánchez-Moreno, Manuel
Mascaró Lazcano, Carmen
Issue Date: 2001
Abstract: Cryptosporidium parvum oocysts are the infective stages responsible for transmission and survival of the organism in the environment. In the present work we show that the oocyst wall, far from being a static structure, is able to incorporate antigens by a mechanism involving vesicle fusion with the wall, and the incorporation of the antigen to the outer oocyst wall. Using immunoelectron microscopy we show that the antigen recognized by a monoclonal antibody used for diagnosis of cryptosporidiosis (MerifluorÒ, Meridian Diagnostic Inc.) could be found associated with vesicles in the space between the sporozoites and the oocysts wall, and incorporated to the outer oocyst wall by an unknown mechanism.
Publisher: Instituto Oswaldo Cruz
Keywords: Cryptosporidium
Oocyst wall
URI: http://hdl.handle.net/10481/32451
ISSN: 0074-0276
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Entrala, E.; et al. Antigen Incorporation on Cryptosporidium parvum Oocyst Walls. Memórias do Instituo Oswaldo Cruz, 96(2): 233-235 (2001). [http://hdl.handle.net/10481/32451]
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