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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/31911

Title: Entry, dispersion and differentiation of microglia in the developing central nervous system
Authors: Navascués Martínez, Julio
Calvente Iglesias, Ruth
Marín-Teva, José Luis
Cuadros Ojeda, Miguel Ángel
Issue Date: 2000
Abstract: Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream. Once in the nervous parenchyma, microglial cells increase in number and disperse throughout the CNS; these cells finally differentiate to become fully ramified microglial cells. In this article we review present knowledge on these phases of microglial development and the factors that probably influence them.
Publisher: Academia Brasileira de Ciências
Keywords: Microglia
Hematopoietic lineage
Meninges
Migration
Proliferation
URI: http://hdl.handle.net/10481/31911
ISSN: 0001-3765
1678-2690
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Navascués, J.; et al. Entry, dispersion and differentiation of microglia in the developing central nervous system. Anais da Academia Brasileira de Ciencias, 72(1): 91-102 (2000). [http://hdl.handle.net/10481/31911]
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