TY - JOUR AU - Dao, Khanh K. AU - Pey Rodríguez, Ángel Luis AU - Gjerde, Anja Underhaug AU - Teigen, Knut AU - Byeon, In-Ja L. AU - Døskeland, Stein O. AU - Gronenborn, Angela M. AU - Martínez, Aurora PY - 2011 SN - 1932-6203 UR - http://hdl.handle.net/10481/31128 AB - [Background] The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP. Considering its highly dynamic nature, the protein is... LA - eng PB - Public Library of Science (PLOS) KW - Atomic force microscopy KW - Biochemical simulations KW - Cricular dichroism spectroscopy KW - Crystal structure KW - Fluorescence KW - Fluorescence microscopy KW - Protein structure KW - Thermal stability TI - The Regulatory Subunit of PKA-I Remains Partially Structured and Undergoes β-Aggregation upon Thermal Denaturation ER -