Grosulfeimin and new related guaianolides from cynara scolymus L. Barbetti, P. Chiappini, I. Fardella, G. Grandolini, G. Cynara scolymus L. Sesquiterpene lactones Sulfonyl Guaianolides Guaianolides Three new guaianolides 11-H-13-rnethylsulfonylgrosheirnin 5 (Grosulfeirnin), 8-deoxy-11, 13-dihydroxygrosheimin 7 and 8-deoxy-11-hydroxy-13-chlorogrosheimin 8 have been isolated from the leaves of Cynara scolymus L. Besides, 8-epigrosheirnin 9 has been isolated for the ftrst time frorn this source. The structures were deterrnined by spectroscopical rnethods and by chernical correlations. 2023-07-11T11:12:47Z 2023-07-11T11:12:47Z 1991-12-20 info:eu-repo/semantics/article Barbetti, P.; et al. Grosulfeimin and new related guaianolides from cynara scolymus L. Ars Pharm, 433-439 (1992). Disponible en: https://revistaseug.ugr.es/index.php/ars/article/view/25818 2340-9894 https://hdl.handle.net/10481/83584 spa http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Universidad de Granada, Facultad de Farmacia.