Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up Torres Collado, Laura Cano Ibáñez, Naomi Bueno Cavanillas, Aurora Dietary diversity score Mortality Cardiovascular disease Cancer The VNS study was supported by a grant from the Direccion General de Salud Publica, Generalitat Valenciana 1994 and the Fondo Investigacion Sanitaria (FIS 00/0985). This study has also received support from the Instituto de Salud Carlos III and FEDER funds (FIS PI13/00654) and Generalitat Valenciana AICO/2021/347. We evaluated the relationship between the dietary diversity score (DDS) and all-cause, CVD and cancer mortality in an adult Mediterranean population. We analyzed the data of 1540 participants from the Valencia Nutrition Survey. The DDS was estimated using a validated food frequency questionnaire and was categorized into quartiles (Q), where the first quartile indicates the lowest dietary diversity. Deaths were ascertained during an 18-year follow-up period. Cox regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI). There were 403 deaths during the follow-up period (40% due to CVD). An inverse association was observed between the DDS and all-cause and CVD mortality. Compared with participants in the lowest DDS quartile (Q1), participants in the highest DDS quartile (Q4) showed 32% and 45% less risk of death for all-cause and CVD mortality, in sex- and age-adjusted models, respectively. Regarding the food groups in the DDS, an inverse association was identified between total vegetable consumption diversity and all-cause and CVD mortality in the highest quartiles, (Q3 vs. Q1, HR: 0.70; 95% CI: 0.50, 0.99) and (Q4 vs. Q1, HR: 0.52; 95% CI: 0.30, 0.91), respectively. This study suggests that a higher diversity in food intake, particularly in vegetables, may be associated with a lower risk of all-cause and CVD mortality. This association should be further investigated in other wider populations. 2022-05-11T06:56:07Z 2022-05-11T06:56:07Z 2022-04-11 info:eu-repo/semantics/article Torres-Collado, L... [et al.]. Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up. Nutrients 2022, 14, 1583. [https://doi.org/10.3390/nu14081583] http://hdl.handle.net/10481/74790 10.3390/nu14081583 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI