Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review Rueda Robles, Ascensión Rubio Tomás, Teresa Plaza Díaz, Julio Álvarez Mercado, Ana Isabel Helicobacter pylori Diet Gastrointestinal microbiota Experimental models Therapeutic approaches Julio Plaza-Diaz is part of the "UGR Plan Propio de Investigacion 2016" and the "Excellence actions: Unit of Excellence on Exercise and Health (UCEES), University of Granada". He is likewise supported by a grant to postdoctoral researchers at foreign universities and research centers from the "Fundacion Ramon Areces", Madrid, Spain. Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. This bacterium is responsible for long-term complications of gastric disease. The conjunction of host genetics, immune response, bacterial virulence expression, diet, micronutrient availability, and microbiome structure influence the disease outcomes related to chronic H. pylori infection. In this regard, the consumption of unhealthy and unbalanced diets can induce microbial dysbiosis, which infection with H. pylori may contribute to. However, to date, clinical trials have reported controversial results and current knowledge in this field is inconclusive. Here, we review preclinical studies concerning the changes produced in the microbiota that may be related to H. pylori infection, as well as the involvement of diet. We summarize and discuss the last approaches based on the modulation of the microbiota to improve the negative impact of H. pylori infection and their potential translation from bench to bedside. 2021-09-20T11:08:54Z 2021-09-20T11:08:54Z 2021-07-10 info:eu-repo/semantics/article Rueda-Robles, A... [et al.]. Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review. Pathogens 2021, 10, 875. [https://doi.org/10.3390/pathogens10070875] http://hdl.handle.net/10481/70302 10.3390/pathogens10070875 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI