Reductions in blood concentrations of persistent organic pollutants in the general population of Barcelona from 2006 to 2016 Porta, Miquel Arrebola Moreno, Juan Pedro Human biomonitoring Health survey Persistent organic pollutants (POPs) Pesticide residues Environmental pollutants Environmental exposure/human samples Polybrominated diphenyl ethers (PDBEs) Polycyclic aromatic hydrocarbons (PAHs) The work was supported in part by research grants from Instituto de Salud Carlos III, Ministry of Health, Government of Spain - cofunded by FEDER (FIS PI13/00020, FIS PI17/00088, and CIBER de Epidemiologia y Salud Publica CIBERESP) ; the Hospital del Mar Medical Research Institute (IMIM) , Barcelona; the Government of Catalonia (2014 SGR 1012, 2017 SGR 439) ; Fundacio La Marato de TV3 (20132910) ; and the CRUE-Santander Fondo Supera Covid19 (15072020) . UB was supported by the Office of the Director of the National Institutes of Health under award number DP5OD26429. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Background: Few cities in the world biomonitor changes in human levels of persistent organic pollutants (POPs) through periodic health surveys representative of the general population. Objectives: To analyze changes in serum concentrations of POPs in Barcelona from 2006 to 2016, and to analyze socio-demographic correlates of concentrations of 62 POPs in 2016. Methods: Participants in the Barcelona Health Surveys of 2006 and 2016 (N = 231 and 240, respectively) were interviewed face-to-face, gave blood, and underwent a physical exam. POPs were analyzed by gas chromatography mass spectrometry. Results: Concentrations of all nine most prevalent compounds decreased markedly during the 10-years . Reductions occurred in almost all sex, age and BMI subgroups. For most organochlorine compounds the reduction was larger in women than men (for HCB, & minus;77% and & minus; 62%, respectively). For beta-HCH, PCBs, naphthalene and phenanthrene the decrease was larger in the younger groups. Large reductions in concentrations of PCBs and DDE were observed in individuals with normal weight but not in individuals with obesity. Conclusions: While concentrations of most POPs are decreasing in Barcelona, significant sociodemographic differences in such reductions warrant strengthening public and private policies towards groups making slower progress. A relevant component of the success in the current decreasing is a reduction of differences (convergence) by gender. 2021-06-15T07:24:58Z 2021-06-15T07:24:58Z 2021-03-02 info:eu-repo/semantics/article Miquel Porta, José Pumarega, Luis A. Henríquez-Hernández, Magda Gasull, Xavier Bartoll, Juan P. Arrebola, Eva Morales, Jesús Ibarluzea, Juan Alguacil, Usama Bilal, Octavio P. Luzardo, Reductions in blood concentrations of persistent organic pollutants in the general population of Barcelona from 2006 to 2016, Science of The Total Environment, Volume 777, 2021, 146013, ISSN 0048-9697, [https://doi.org/10.1016/j.scitotenv.2021.146013] http://hdl.handle.net/10481/69172 10.1016/j.scitotenv.2021.146013 eng http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Atribución-NoComercial-SinDerivadas 3.0 España Elsevier