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   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/59117">
      <dc:title>Cortical Visual Evoked Potentials and Growth in Infants Fed with Bioactive Compounds-Enriched Infant Formula: Results from COGNIS Randomized Clinical Trial</dc:title>
      <dc:creator>Nieto-Ruiz, Ana</dc:creator>
      <dc:creator>García Santos, José Antonio</dc:creator>
      <dc:creator>G. Bermúdez, Mercedes</dc:creator>
      <dc:creator>Herrnan, Florian</dc:creator>
      <dc:creator>Diéguez Castillo, Estefanía</dc:creator>
      <dc:creator>Sepúlveda Valbuena, Natalia</dc:creator>
      <dc:creator>García García, Salomé</dc:creator>
      <dc:creator>Miranda León, María Teresa</dc:creator>
      <dc:creator>Castellar, Roser de</dc:creator>
      <dc:creator>Rodríguez-Palmero, Maria</dc:creator>
      <dc:creator>Catena Martínez, Andrés</dc:creator>
      <dc:creator>Campoy Folgoso, Cristina</dc:creator>
      <dc:subject>Breastfeeding</dc:subject>
      <dc:subject>Infant formula</dc:subject>
      <dc:subject>Bioactive compounds</dc:subject>
      <dc:subject>Visual evoked potentials</dc:subject>
      <dc:subject>Growth</dc:subject>
      <dc:description>Postnatal nutrition is essential for growth and neurodevelopment. We analyzed the&#xd;
influence of a new enriched-infant formula with bioactive compounds on growth, neurodevelopment,&#xd;
and visual function (VF) in healthy infants during their first 18 months of life. A total of 170 infants&#xd;
were randomized in the COGNIS randomized clinical trial (RCT) to receive a standard infant formula&#xd;
(SF = 85) or a new experimental infant formula supplemented with functional nutrients (EF = 85). As a&#xd;
control, 50 breastfed infants (BF) were enrolled. Growth patterns were evaluated up to 18 months of&#xd;
life; neurodevelopment was assessed by general movements at 2, 3, and 4 months; VF was measured by&#xd;
cortical visual evoked potentials at 3 and 12 months. No differences in growth and neurodevelopment&#xd;
were found between groups. Regarding VF, SF and EF infants presented prolonged latencies and&#xd;
lower amplitudes in the P100 wave than BF infants. In the EF group, a higher percentage of infants&#xd;
presented response at 7 1/2' of arc at 12 months compared to 3 months of age; a similar proportion of BF&#xd;
and EF infants presented responses at 7 1/2' of arc at 12 months of age. Early nutritional intervention&#xd;
with bioactive compounds could narrow the gap in growth and neurodevelopment between breastfed&#xd;
and formula-fed infants.</dc:description>
      <dc:date>2020-01-24T10:31:30Z</dc:date>
      <dc:date>2020-01-24T10:31:30Z</dc:date>
      <dc:date>2019-10-14</dc:date>
      <dc:type>info:eu-repo/semantics/article</dc:type>
      <dc:identifier>Nieto-Ruiz, A., García-Santos, J. A., Bermúdez, M. G., Herrmann, F., Diéguez, E., Sepúlveda-Valbuena, N., ... &amp; Catena, A. (2019). Cortical Visual Evoked Potentials and Growth in Infants Fed with Bioactive Compounds-Enriched Infant Formula: Results from COGNIS Randomized Clinical Trial. Nutrients, 11(10), 2456.</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/59117</dc:identifier>
      <dc:identifier>10.3390/nu11102456</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
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