Rapid detection and identification of strains carrying carbapenemases directly from positive blood cultures using MALDI-TOF MS
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Hoyos-Mallecot, Yannick; Riazzo, C.; Miranda-Casas, C.; Rojo Martín, María Dolores; Gutiérrez Fernández, José; Navarro Marí, José MaríaEditorial
Elsevier
Materia
MALDI-TOF Carbapenemases Blood culture
Date
2014-10Referencia bibliográfica
Hoyos-Mallecot Y, Riazzo C, Miranda-Casas C, Rojo-Martín MD, Gutiérrez-Fernández J, Navarro-Marí JM. Rapid detection and identification of strains carrying carbapenemases directly from positive blood cultures using MALDI-TOF MS. Journal of Microbiological Methods 105 (2014) 98–101. http://dx.doi.org/10.1016/j.mimet.2014.07.016
Abstract
MALDI-TOF MS has been evaluated to detect carbapenemases activity and pathogen identification directly from positive blood cultures. 21 non-carbapenemase producers and 19 carbapenemase producers Enterobacteriaceae and Pseudomonas aeruginosa strains were included in the study. This technique is simple and detects carbapenemases in 4.5h with high sensitivity and specificity.