Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system

Marín Romero, Antonio; Sánchez Martín, Rosario María; Díaz Mochón, Juan José

doi:10.1016/j.talanta.2020.121265

Marin-romero-2020-Amplification-free-profiling-of-mic (1).pdf (2.120Mb)

Identificadores

URI: https://hdl.handle.net/10481/88615

DOI: 10.1016/j.talanta.2020.121265

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Editorial

Elsevier

Fecha

2020-06-29

Referencia bibliográfica

Marín-Romero A, Tabraue-Chávez M, Dear JW, Sánchez-Martín RM, Ilyine H, Guardia-Monteagudo JJ, Fara MA, López-Delgado FJ, Díaz-Mochón JJ, Pernagallo S. Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system. Talanta. 2020 Nov 1;219:121265. doi: 10.1016/j.talanta.2020.121265. Epub 2020 Jun 29. PMID: 32887156.

Resumen

Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.

Colecciones

CTS987 - Artículos

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