Intracellular delivery of a catalytic organometallic complex
Metadata
Show full item recordAuthor
Indrigo, Eugenio; Clavadetscher, Jessica; Chankeshwara, Sunay V.; Megía Fernández, Alicia; Lilienkampf, Annamaria; Bradley, MarkEditorial
The Royal Society of Chemistry
Materia
Bioorthogonal Palladium Profluorophore Cell-penetrating peptide
Date
2017Referencia bibliográfica
Chem Commun 2017, 53, 6712-6715
Abstract
A homogeneous carbene-based palladium catalyst was conjugated to a cell-penetrating peptide, allowing intracellular delivery of catalytically active Pd complexes that demonstrated bioorthogonal activation of a profluorophore within prostate cancer cells.