Encapsulation of Bioactive Peptides by Spray-Drying and Electrospraying
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Berraquero García, Carmen; Pérez Gálvez, Antonio Raúl; Espejo Carpio, Francisco Javier; Guadix Escobar, Antonio María; Guadix Escobar, Emilia María; García Moreno, Pedro JesúsEditorial
MDPI
Materia
Nano/microencapsulation Spray drying Electrospraying Coaxial encapsulation Bioactive peptides Protein hydrolysates
Date
2023-05-15Referencia bibliográfica
Berraquero-García, C.; Pérez-Gálvez, R.; Espejo-Carpio, F.J.; Guadix, A.; Guadix, E.M.; García-Moreno, P.J. Encapsulation of Bioactive Peptides by Spray-Drying and Electrospraying. Foods 2023, 12, 2005. [https://doi.org/10.3390/foods12102005]
Sponsorship
I+D+i project PID2020-114137RBI00 funded by MCIN/AEI/10.13039/501100011033/Abstract
Bioactive peptides derived from enzymatic hydrolysis are gaining attention for the production
of supplements, pharmaceutical compounds, and functional foods. However, their inclusion
in oral delivery systems is constrained by their high susceptibility to degradation during human
gastrointestinal digestion. Encapsulating techniques can be used to stabilize functional ingredients,
helping to maintain their activity after processing, storage, and digestion, thus improving their
bioaccessibility. Monoaxial spray-drying and electrospraying are common and economical techniques
used for the encapsulation of nutrients and bioactive compounds in both the pharmaceutical and
food industries. Although less studied, the coaxial configuration of both techniques could potentially
improve the stabilization of protein-based bioactives via the formation of shell–core structures. This
article reviews the application of these techniques, both monoaxial and coaxial configurations, for
the encapsulation of bioactive peptides and protein hydrolysates, focusing on the factors affecting
the properties of the encapsulates, such as the formulation of the feed solution, selection of carrier
and solvent, as well as the processing conditions used. Furthermore, this review covers the release,
retention of bioactivity, and stability of peptide-loaded encapsulates after processing and digestion.