Screening antibiotics: industrial research by CEPA and Merck in the 1950s
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Show full item recordAuthor
Santesmases, María JesúsEditorial
Universidad de Granada
Materia
Antibiotic screening CEPA Spain Factory system and research Antonio Gallego Selman Waksman Screening de antibióticos España Sistema fabril e investigación
Date
2011Referencia bibliográfica
Santesmases, María Jesús. «Screening antibiotics : industrial research by CEPA and Merck in the 1950s». Dynamis: Acta Hispanica ad Medicinae Scientiarumque Historiam Illustrandam, 2011, Vol. 31, Núm. 2, p. 407-427, https://raco.cat/index.php/Dynamis/article/view/253045.
Sponsorship
Spanish ministry of Science and Innovation (FFI2009-07522); ESF Research networking program DRUGSAbstract
This article is an account of a screening programme in search of new antibiotics
established by CEPA (Compañia Española de Penicilinas y Antibióticos) and Merck in Madrid
in 1954. An exploration of the genealogy for such a programme, its narratives and practices,
shows that the main inspiration for this programme was the factory system of production,
on the one hand, and Selman Waksman’s research agenda on microorganisms of the soil,
on the other. In this article, the relationship between industrial production of antibiotics
and the research program aimed at identifying new candidate drugs is examined. I suggest
that this screening program in search of new antibiotics was organised like industrial manufacturing.
The research objects and tools came, both materially and conceptually, from
industrial production: a line of artisanship put together in order to obtain a product with
the collaboration of every member of the production line. Following the style developed by
Selman Waksman in Rutgers, the screening program evaluated samples manually, and the
microbiological skills were enhanced with every test. The Madrid team’s practice of applying
instructions for use led to circulation of knowledge and practices, including research material
and microbiological methods.