The Effect of Therapeutic Hypothermia after Cardiac Arrest on the Neurological Outcome and Survival—A Systematic Review of RCTs Published between 2016 and 2020
Metadatos
Afficher la notice complèteAuteur
Colls Garrido, Christian; Riquelme Gallego, Blanca; Sánchez García, Juan Carlos; Cortés Martín, Jonathan; Montiel Troya, María; Rodríguez Blanque, RaquelEditorial
MDPI
Materia
Induced hypothermia Cardiac arrest Survival rates Critical care
Date
2021-11-11Referencia bibliográfica
Colls Garrido, C... [et al.]. The Effect of Therapeutic Hypothermia after Cardiac Arrest on the Neurological Outcome and Survival—A Systematic Review of RCTs Published between 2016 and 2020. Int. J. Environ. Res. Public Health 2021, 18, 11817. [https://doi.org/10.3390/ijerph182211817]
Résumé
Therapeutic hypothermia is a treatment used for patients who have suffered cardiorespiratory
arrest and remain conscious after the recovery of spontaneous circulation. However, its
effectiveness is controversial. The objective of this systematic review is to summarize the scientific
evidence available about the effect of therapeutic hypothermia on neurological status and survival
in this type of patients. Methodology: A primary search in CINAHL, CUIDEN, Pubmed, Web of
Science, and Scopus databases was carried out. Randomized clinical trials (RCT) published from 2016
to 2020 were selected. Results: 17 studies were selected for inclusion and most relevant data were
extracted. Methodological quality was assessed by the RoB tool. Conclusions: Although therapeutic
hypothermia is a safe technique with few adverse and manageable effects, it has not shown to
improve survival rate and neurological status of adult nor pediatric patients. It is possible that its
positive effect on neuroprotection could be achieved only by preventing hyperthermia although
further investigation is needed.