A Feasibility and Efficacy Randomized Controlled Trial of Two Exercise Programs in Severe AECOPD Patients with Resting Hypoxemia
Metadatos
Mostrar el registro completo del ítemAutor
López López, Laura; Calvache Mateo, Andrés; Rodríguez-Torres, Janet; Granados Santiago, María; Ortiz Rubio, Araceli; Valenza, Marie CarmenEditorial
MDPI
Materia
COPD Chronic Obstructive Pulmonary Disease Exacerbation Exercise training Hypoxemia NEMS
Fecha
2021Referencia bibliográfica
López-López, L.; Calvache-Mateo, A.; Rodríguez-Torres, J.; Granados-Santiago, M.; Ortiz-Rubio, A.; Valenza, M.C. A Feasibility and Efficacy Randomized Controlled Trial of Two Exercise Programs in Severe AECOPD Patients with Resting Hypoxemia. Healthcare 2021, 9, 1102. https://doi.org/10.3390/healthcare 9091102
Patrocinador
FPU grant (FPU: 17/00408) of the Spanish Ministry of Education (Spain); FPU (“Formación Profesorado Universitario”) grant (FPU: 19/02609) of the Spanish Ministry of Education; FPU (“Formación Profesorado Universitario”) grant (FPU: 16/01531) of the Spanish Ministry of EducationResumen
Resting hypoxemia is the most severe stage of Chronic Obstructive Pulmonary Disease
(COPD). Due to their impairments during the exacerbation, these patients are limited to traditional
exercise rehabilitation and are excluded from the majority of the studies. The aim of this study
was to assess the feasibility and the efficacy of two exercise programs in Acute Exacerbation of
COPD (AECOPD) patients with resting hypoxemia. In this randomized clinical trial, patients
hospitalized due to an acute exacerbation of COPD with hypoxemia at rest were included. Patients
were randomly assigned into three groups. A Control Group (pharmacological treatment), a Global
Exercise Group (GEG), and a Functional Electrostimulation Group (FEG). Patients were treated
during the hospitalization period. The main outcomes were lower limb strength (assessed by a
dynamometer), balance (assessed by the one leg standing balance test), health related quality of
life (assessed by the EQ-5D), adverse events and adherence. At the end of the intervention, there
were significant differences in all the variables in favour of the experimental groups (p < 0.05). We
concluded that conducting an exercise program is feasible and improves lower limb strength, balance,
and health related quality of life in AECOPD patients with resting hypoxemia.