Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights
Metadatos
Afficher la notice complèteAuteur
Rodríguez Sojo, María Jesús; Ruiz Malagón, Antonio Jesús; Rodríguez Cabezas, María Elena; Gálvez Peralta, Julio Juan; Rodríguez Nogales, AlbaEditorial
MDPI
Materia
Probiotic Limosilactobacillus fermentum CECT5716 Immunomodulation Dysbiosis Mechanism of action Gastrointestinal diseases Microbiota
Date
2021-03-21Referencia bibliográfica
Rodríguez-Sojo, M.J.; Ruiz-Malagón, A.J.; Rodríguez-Cabezas, M.E.; Gálvez, J.; Rodríguez-Nogales, A. Limosilactobacillus fermentum CECT5716: Mechanisms and Therapeutic Insights. Nutrients 2021, 13, 1016. [https://doi.org/10.3390/nu13031016]
Patrocinador
Junta de Andalucia CTS 164; Instituto de Salud Carlos III European Commission PI19/01058; European CommissionRésumé
Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limosilactobacillus fermentum CECT5716 has become one of the most promising probiotics and it has been described to possess potential beneficial effects on inflammatory processes and immunological alterations. Different studies, preclinical and clinical trials, have evidenced its anti-inflammatory and immunomodulatory properties and elucidated the precise mechanisms of action involved in its beneficial effects. Therefore, the aim of this review is to provide an updated overview of the effect on host health, mechanisms, and future therapeutic approaches.